Influence of adipose tissue mass on bone mass in an overweight or obese population: systematic review and meta-analysis
Dolan, Eimear, Swinton, Paul, Sale, Craig, HEALY, Aoife and O'Reilly, John (2017) Influence of adipose tissue mass on bone mass in an overweight or obese population: systematic review and meta-analysis. Nutrition Reviews, 75 (10). ISSN 0029-6643
This is the latest version of this item.
Text
Supplementary Table 1.docx - Supplemental Material Available under License Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). Download (23kB) |
|
Text
Figure 1.doc - Supplemental Material Available under License Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). Download (43kB) |
|
Text
NR_Manuscript_Final.docx - AUTHOR'S ACCEPTED Version (default) Available under License Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0). Download (249kB) |
Abstract or description
Context
The scientific literature shows conflicting evidence about the relationship between adiposity and bone mass in overweight and obese populations.
Objective
The aim of this review was to quantify the correlation between adipose mass (absolute and relative) and bone mineral density (BMD) in overweight and obese populations.
Data Sources
Three databases were searched electronically. In addition, reference lists of relevant articles were screened.
Study Selection
A total of 16 studies, comprising 2587 participants and 75 correlation coefficients were selected for inclusion in the review.
Data Extraction
Data were extracted from each study using a standardized form.
Results
Multilevel modeling indicated opposing relationships between BMD and adiposity: absolute adiposity correlated positively, and relative adiposity negatively, with BMD. Sex and age were the primary moderators of these relationships. Strong evidence supported a negative relationship between relative adipose mass and BMD in men (R = −0.37; 95%CI, −0.57 to −0.12) and in those aged less than 25 years (R = −0.28; 95%CI, −0.45 to −0.08).
Conclusion
To prevent bone loss in overweight and obese populations, nutrition- and exercise-based interventions that focus on a controlled reduction of adipose mass with concomitant preservation of lean mass are recommended. Systematic Review Registration: PROSPERO no. CRD42015024313.
Item Type: | Article |
---|---|
Faculty: | School of Life Sciences and Education > Sport and Exercise |
Depositing User: | Aoife HEALY |
Date Deposited: | 03 Oct 2017 11:24 |
Last Modified: | 24 Feb 2023 13:48 |
URI: | https://eprints.staffs.ac.uk/id/eprint/3821 |
Available Versions of this Item
- Influence of adipose tissue mass on bone mass in an overweight or obese population: systematic review and meta-analysis. (deposited 03 Oct 2017 11:24) [Currently Displayed]
Actions (login required)
View Item |