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Clustering Analysis of Long-Term Cardiovascular Complications in COVID-19 Patients

Sadegh-Zadeh, Seyed-Ali, Soleimani Mamalo, Alireza, Saadat, Shayan, Behnemoon, Mahsa, Ojarudi, Masoud, Gharebaghi, Naser, Pashaei, Mohammad Reza and Hajizadeh, Reza (2025) Clustering Analysis of Long-Term Cardiovascular Complications in COVID-19 Patients. Frontiers in Biomedical Signal Processing, 1 (1). pp. 1-23.

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Official URL: https://www.icck.org/article/abs/fbsp.2025.731159

Abstract or description

This study employs K-means clustering to analyze long-term cardiovascular complications in COVID-19 patients through ECG parameters, demographics, comorbidities, and hospitalization data. Three distinct clusters emerged: Cluster 0 (moderate heart rate variability/ICU admissions), Cluster 1 (lower variability/admissions), and Cluster 2 (higher variability/admissions, indicating elevated risk). Bootstrap validation confirmed model robustness, supported by high silhouette scores and consistent cluster labels. The novel integration of multimodal data with machine learning revealed hidden cardiovascular outcome patterns, demonstrating clinical utility for risk stratification. Findings underscore the value of clustering techniques in personalizing post-COVID care and optimizing resource allocation for high-risk survivors.

Item Type: Article
Uncontrolled Keywords: COVID-19; cardiovascular complications; clustering analysis; K-means; ECG parameters
Faculty: School of Digital, Technologies and Arts > Computer Science, AI and Robotics
Depositing User: Ali SADEGH ZADEH
Date Deposited: 12 Feb 2026 14:52
Last Modified: 12 Feb 2026 14:52
URI: https://eprints.staffs.ac.uk/id/eprint/9537

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